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Case Report
A case of adolescent Kawasaki disease with Epstein-Barr virus-associated infectious mononucleosis complicated by splenic infarction
Byeong Sam Choi, Bo Sang Kwon, Gi Beom Kim, Yoon Kyung Jeon, Jung-Eun Cheon, Eun Jung Bae, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 2009;52(9):1029-1034.   Published online September 15, 2009
Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology that affects children. There are few reports that describe the Epstein-Barr virus (EBV) as the possible infectious agent of KD. Here, we describe a case of KD in a 15- year-old boy complicated with giant coronary artery aneurysms, pericardial effusion, and splenic infarction. The clinical course of KD was...
Original Article
Epidemiologic study of Kawasaki disease in 6 months old and younger infants
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Joon Sung Lee, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2008;51(12):1320-1323.   Published online December 15, 2008
Purpose : The aim of this study was to investigate the epidemiologic status of Kawasaki disease (KD) in infants ≤6 months of age. Methods : For the epidemiologic study of KD in Korea, data from 22,674 KD patients were collected from 1997 to 2005 on a 3-year basis by a retrospective survey. From this survey, data of 1,739 KD patients ≤6...
Clinical and Epidemiologic Study of Kawasaki Disease in Children 8 Years of Age and Older
Yong Won Park, Ji Whan Han, In Sook Park, Chang Hwi Kim, Sung Ho Cha, Jae Sook Ma, Tae Chan Kwon, Sang Bum Lee, Chul Ho Kim, Heung Jae Lee, Yong Soo Yun
Clin Exp Pediatr. 2005;48(10):1139-1142.   Published online October 15, 2005
Purpose : The aim of this study was to investigate the epidemiologic and clinical profiles of Kawasaki disease(KD) in children 8 years of age and older. Methods : For the epidemiologic study of KD in Korea, data of total 15,692 KD patients were collected from 1994 to 2002 on a 3 year basis, by the retrospective survey. Among them, data of...
Follow-up Study of Children with Anthracycline Cardiotoxicity
Hyok Joo Kwon, Young Hwan Song, Soo Jung Kang, Hyoung Jin Kang, Hyoung Soo Choi, Eun Jung Bae, Hee Young Shin, Chung Il Noh, Yong Soo Yun, Hyo Seop Ahn
Clin Exp Pediatr. 2003;46(3):242-249.   Published online March 15, 2003
Purpose : We studied the relationship between anthracycline cumulative dose and anthracycline cardiotoxicity in childhood cancer and followed up 40 children with anthracycline cardiotoxicity. Methods : A retrospective study was performed in 154 children who received anthracycline chemotherapy between January 1995 to December 2000. Cardiotoxicity was defined when the left ventricular fractional shortening(FS) was below 26%; it was divided into two...
Diagnostic Assessment of Pulmonary Atresia with Ventricular Septal Defect; Comparison of Echocardiogram with Cardiac Angiography
Jung Yun Choi, Jeong Jin Yu, Soo Jung Kang, Jae Seong Son, Young Mee Seo, Jin Young Song, Ho Sung Kim, Eun Jung Bae, Chung Il Noh, Yong Soo Yun
Clin Exp Pediatr. 2001;44(2):154-160.   Published online February 15, 2001
Purpose : Patients with pulmonary atresia with ventricular septal defects(PAVSD) have been a formidable surgical challenge. The source of pulmonary blood flow and vascular architecture are important in managing the surgical process. This study aimed to evaluate the usefulness of echocardiography in this process. Methods : This study was prospectively designed to define the role of echocardiography in PAVSD. Non-invasive evaluations...
Infective Endocarditis in Children : Review of 35 Cases over 11 Years(1987-1997)
Jeong Jin Yu, Young Ho Kwak, Jung-Youn Hong, He Sun Jung, Jin Young Song, Hoan Jong Lee, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 2000;43(4):526-534.   Published online April 15, 2000
Purpose : Infective endocarditis(IE) is a serious complication in children with structural heart disease. We reviewed 35 cases of IE to identify the recent changes in the pattern of preexisting heart diseases, the spectrum of causative organisms and prognosis. Methods : The clinical records of children diagnosed as IE at the Seoul National University Children`s Hospital from January 1987 through December...
Cell Proliferation and Apoptosis in Heart of Trisomy 16 in Mice
Eun Jung Bae, Yong Soo Yun, Jung Sun Kim, Jeong-Wook Seo
Clin Exp Pediatr. 1999;42(5):621-630.   Published online May 15, 1999
Purpose : Although abnormal developments of cushion and atrioventricular septum have been suggested, the exact mechanism for the development of atrioventricular septal defect is not well known. We aimed to identify the role of cell proliferation and apoptosis on cardiac morphogenesis in trisomy 16 mice(an animal model for Down's syndrome in human). Methods : We examined the difference in cardiac...
The Relationship between Total Serum IgE, Allergen-Specific IgE, and Skin Prick Test in Children with Atopic Asthma
Myung Hyun Lee, Jin Hwa Cheong, Young Yull Koh, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1999;42(3):403-411.   Published online March 15, 1999
Purpose : Skin prick test and determination of allergen-specific IgE antibodies in serum are methods commonly used to diagnose allergies. Several studies indicate that skin test and specific IgE have roughly the same diagnostic precision, although discrepancies exist. The objective of this study was to evaluate the influence of total serum IgE on the relation between skin prick test and...
Microdeletion of Chromosome 7 in Williams Syndrome and Supravalvular Aortic Stenosis
Ho Sung Kim, Yoon Sung Kang, Kyung Hyo Kim, Young Mi Hong, Yong Soo Yun, Kwang Ho Lee
Clin Exp Pediatr. 1999;42(1):47-59.   Published online January 15, 1999
Purpose : Williams syndrome is characterized by supravalvular aortic stenosis, mental retardation and peculiar facial appearance. Its genetic etiology is considered to be a hemizygotic deletion in Chromosome 7q11.23, which includes the elastin gene. We examined the hemizygotic deletion of Chromosome 7q11.23 in 12 Korean Williams syndrome patients and 8 patients with isolated supravalvular aortic stenosis and performed deletion mapping...
The Assessment of Pulmonary Parenchymal Damage in Congenital Heart Disease using Lung Perfusion Scan
Hong Ryang Gil, Jae Goo Lee, Kang Uk Lee, Eun Ho Yi, Myung Ja Yun, Chung Il Noh, Jung Yeon Choi, Yong Soo Yun
Clin Exp Pediatr. 1998;41(5):640-645.   Published online May 15, 1998
Purpose : In acyanotic congenital heart disease of children with left to right shunt, 99mTc- Macroaggregate albumin(MAA) was employed to determine the scintigraphic severity of pulmonary parenchymal damage. Methods : These data of lung perfusion scan using 99mTc-MAA were compared with hemodynamic values obtained from cardiac catheterization. Results : The mean Pulmonary arterial pressure(≥30mmHg), total pulmonary resistance(≥2 Wood unit)...
Interim Results of Single Stage Operation for Coarctation of Aorta with Large Ventricular Septal Defect in Infancy
Ho Sung Kim, Chung Il Noh, Yong Soo Yun, Jung Yun Choi, Jeong Ryul Lee, Yong Jin Kim, Joon Ryang Roh
Clin Exp Pediatr. 1997;40(9):1250-1257.   Published online September 15, 1997
Purpose : There are controversies in the operative methods of aorta with ventricular septal defect in infancy. Recent results of single stage operation for coarctation of aorta with intracardiac defects were regarded as comparable to staged operation. We evaluated our interim results after single stage operation for coarctation of aorta with large ventricular septal defect in infancy. Methods : Twenty six infants who had received...
Case Report
A Report of Familial Dilated Cardiomyopathy
Ee Kyung Kim, Jung Yun Choi, Chung Il Noh, Yong Soo Yun, Ho Sung Kim, Myung Hyun Lee, In Kyu Kim
Clin Exp Pediatr. 1997;40(6):857-861.   Published online June 15, 1997
Two families of dilated cardiomyopathy are reported. In the first family, two sons were affected. The elder child presented with congestive symptoms at the age of 5 months and was diagnosed to have dilated cardiomyopathy. The etiology of cardiomyopathy was thought to be idiopathic until his younger brother presented with near collapse at the age of 5 days and was diagnosed to have the...
Original Article
Intermediate Term Follow-up Results of Hypertrophic Cardiomyopathy in Children
Eun Jung Cheon, Chung Il Noh, Jae Young Lee, Sun Sung Park, Myung Ja Yun, Hong Ryang Kil, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1997;40(5):641-649.   Published online May 15, 1997
Purpose : Hypertrophic cardiomyopathy(HCMP) is a primary cardiac muscular disease with high risk of sudden cardiac death. This study is performed to understand the clinical features of children with HCMP. Methods : Retrospective analysis of the medical records of the patients diagnosed at Seoul National University Children's Hospital between October 1985 and June 1996 was done. Excluded the patients who had...
Experience of Stent Implantation in Branch Pulmonary Artery Stenosis of the Congenital Heart Diseas
Yong Soo Yun, Eun Jung Cheon, Ho Sung Kim, Chung Il Noh, Jung Yun Choi
Clin Exp Pediatr. 1997;40(3):343-351.   Published online March 15, 1997
Purpose : Branch pulmonary artery stenosis remains a clinically challenging lesion. Results of surgical angioplasty are rarely rewarding, and balloon angioplasty is not uniformly successful. So, endovascular stent has been applied recently to these lesions. But this new modality has not been full yevaluated. The aim of this study is to evaluate the short-term result of stent implantation in postoperative branch pulmonary artery stenosis. Methods :...
Case Report
A Case of Pulmonary Artery Sling Associated with Tracheobroncheal Hypoplasia
Yong Han Sun, Ho Sung Kim, Jung Il Noh, Jung Yun Cho, Yong Soo Yun
Clin Exp Pediatr. 1996;39(3):417-422.   Published online March 15, 1996
Pulmonary artery sling is a rare vascular anomaly wherein the left pulmonary artery arises from the right pulmonary artery and then traverses between the esophagus and the trachea toward the hilum of the left lung. Associated anomalies are common, particularly those of the tracheobronchial tree, which have been found in more than 50% of patients. Cardiovascular anomalies such as persistent...
Original Article
Results of the Mechanical Valve Replacement in the Right Side of the Heart in Children
Hyeon Jin Park, Chung Il Noh, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun, Yong Jin Kim
Clin Exp Pediatr. 1995;38(9):1220-1231.   Published online September 15, 1995
Purpose : We performed this study in order to evaluate the outcome of the mechanical valve replacement in the right side of the heart in children. Methods : Retrospective analysis of the clinical records of 26 patients who had undergone a right sided valve replacement between October 1986 and September 1992 at Seoul National University Children뭩 Hospital. Results : Twenty six children...
Double Chambered Right Ventricle-Review of Clinical Findings
Jin Young Song, Jun Tac Ko, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Yong Soo Yun
Clin Exp Pediatr. 1995;38(7):914-921.   Published online July 15, 1995
Purpose : The DCRV is a cardiac anomaly in which the right ventricle is divided into two dif-ferent pressure chambers by aberrant hypertrophied muscle bundles arising from the lower infundibular septal region. DCRV may be associated with other congenital cardiac anomalies and surgical treatment is required because we know that this obstruction is progressive. In this report, we reviewed clinically...
Fetal Cardiac Malformation : types and associated anomalies
Ho Sung Kim, Jeong Wook Seo, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1995;38(6):811-818.   Published online June 15, 1995
Purpose : The relative incidence of fetal cardiac anomalies and associated extracardiac anomalies in Korean fetuses were studied. Methods : Findings in fetal echocardiography and autopsy were reviewed using 129 fetuses with cardiac anomalis detected at a gestational period under 38 weeks from 1991 Jan. to 1994 June. Results : The most common fetal cardiac anomaly was isolated atrial septal defect(28 cases...
Midterm Result after Transcatheter Occlusion of Patent Ductus Arteriosus with Rashkind PDA Umbrella Device
Chung Il Noh, Eun Sook Han, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1995;38(5):668-674.   Published online May 15, 1995
Purpose : To evaluate the appropriateness of the transcatheter occlusion with Rashkind um-brella occlusion device Methods : Among the 54 cases who had been tried transcatheter closure of patent ductus ar teriosus from January, 1992 till December, 1993 at Seoul National Univerity Children's Hospital, the first follow-up evaluation with Doppler echocardioram were done in 43 cases at the mean i-nterval of...
Case Report
Isolated Unilateral Pulmonary Vein Atresia
Yun Ae Jeon, Chung Il Noh, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun, Woo Sun Kim, Je Geun Chi
Clin Exp Pediatr. 1995;38(3):409-416.   Published online March 15, 1995
We report four cases of unilateral pulmonary vein atresia without associated congenital intracardiac anomalies to illustrate a part of the clinical and radiological characteristics and its diagnosis. Pulmonary vein atresia was in right side in all cases. Narrowing of contralateral pulmonary vein and pure red cell anemia were combined in one cases. In four cases, initial presentations were hemoptysis and...
Two Cases of Double-Chambered Right Ventricle by Abnomal Muscle Bundles
Hye Young Kang, Jung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1994;37(5):712-717.   Published online May 15, 1994
The double-chambered right ventricle is congenital or acquired cardiac anomaly, which is characterized by aberrent hypertrophied muscular bands that divide the right ventriclar cavity into two different pressure chamber. This anomaly can complicate the natural history of patient with isolated ventricular septal defect. We experienced two cases of acquired DCRV, which confirmed by two separate cardiac catherterization and angiography. The purpose...
Original Article
Cardiac Rhabdomyoma in Children-A Report of 26 Cases
Ho Sung Kim, Youn Woo Kim, Wun Jung Bae, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1994;37(1):61-69.   Published online January 15, 1994
We reviewed 26 cases of Cardiac rhabdomyoma in children which were diagnosed between 1986 and 1991 in Seoul National University Children's Hospital. Twenty-two cases were associated with tuberous sclerosis. Total tumor count was 58 and mean tumor count per patient was 2.23. Their Cardiac rhabdomyoma were diagnosed from fetal period through 12 years after birth. Median age was 9.5 months....
Nonsurgical Closure of Patent Ductus Arteriosus with the Rashkind PDA Occluder System
Yong Soo Yun, Jung Yun Choi, Jung Il Noh
Clin Exp Pediatr. 1993;36(4):550-555.   Published online April 15, 1993
The first successful application of a transcatheter occlusion of patent ductus arteriosus (PDA) was performed in 1977. Since that time, with continuing improvement and modification of the equipment as well as in the implantation technique, a clinical success rate of abont 84% was accomplished. In children's hospital, Seoul National University, since March 1992, 29 children with simple PDA were treated with...
Percutaneous Transluminal Angioplasty in Takayasu's Arteritis
Yong Soo Yun
Clin Exp Pediatr. 1993;36(2):208-213.   Published online February 15, 1993
1)Among the 24 involved vessels, 5 renal arteries and one left suclavian artery were occulded totally and they were not candidate for angioplasty. 2)Four brachiocepholic branches, three renal artery, and two abdominal aorta were short segmental narrowing in nature and they were feasible for balloon dilatation, 3)Eight sites of thoracic or abdominal aorta in 5 patients were involved in diffuse long segment...
Quantitative Assessment of the Diameters of Tricuspid Valve, Mitral Valve and Great Arteries in the Normal Human Fetus -Cross Sectional Echocardiographic Study-
Jung Yun Choi, Kyung Hee Park, Chung Il Noh, Yong Soo Yun, I Seok Kang, Eun Sook Han
Clin Exp Pediatr. 1992;35(11):1566-1572.   Published online November 15, 1992
In order to assess the growth of the mitral valve, tricuspid valve, and the aortic and pulmonary pathways in the normal human fetus, 181 fetal echocardiograms taken from 127 pregnant women (some women had repeated examinations) were analysed. Diameters were measured from cross sectional images and were correlated with gestational period. The diameter ratios of tricuspid valve/mitral valve, aorta/main pulmonary artery,...
Dimension of Normal Coronary Arteries Determined by Cross-Sectional Echocardiograph
Jung Yun Choi, Yong Soo Yun, Chung Il Noh, Jong Un Choi, I Seok Kang
Clin Exp Pediatr. 1992;35(10):1336-1342.   Published online October 15, 1992
In order to determine the normal values of coronary arterial dimensions in children, eighty eight children without any cardiovascular diseases were studied with cross-sectional echocardiography. Age ranged from 1 day to 15 years. Four sites (proximal right coronary artery, left main, left anterior descending, and left circumflex coronary artery) were selected to measure the dimensions. The right coronary artery was measured...
The Comparison of Coronary Arterial Dimensions Measured by Cross-sectional Echocardiography with Values Obtained by Coronary Angiography in Kawasaki Disease
Mi Jin Jung, Jung Yun Choi, Shung Il Noh, Yong Soo Yun, I Seok Kang
Clin Exp Pediatr. 1992;35(8):1102-1106.   Published online August 15, 1992
In order to assess accuracy of cross-sectional echocardiographic measurements of coronary arterial dimension, measured values of coronary arterial dimensions by cross-sectional echocardiography were compared with the angiographic results. Twenty eight patients with Kawasaki diseas (male: female= 3:1, age range, 7 months-8 years) were studied by both coronary arteriography and crossleft anterior descending coronary artery, and left circumflex coronary artery) were...
Case Report
Two Cases of Anomalous Origin of the Right Pulmonary Artery from the Ascending Aorta
Yong Won Park, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Yong Jin Kim, Joon Ryang Rho, Kyung Pil Suh
Clin Exp Pediatr. 1992;35(7):995-1000.   Published online July 15, 1992
Anomalous origin of the pulmonary artery from the ascending aorta is a rare congenital cardiovascular anomaly which usually involves the right pulmonary artery. Because congestive heart failure and the pulmonary vascular obstructive changes develop early in life, early diagnosis and surgical correction are essential. We experienced two cases of anomalous origin of the right pulmonry artery from the ascending aorta; aorticopulmonary septal...
Original Article
Permanent Epicardial Pacing in Pediatric Patients
I Seok Kang, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1992;35(7):933-941.   Published online July 15, 1992
From September 1982 to July 1991, 40 infants and children aged 3 days to 13 years(mean 3.1 years) underwent implantation of 45 cardiac pacemakers using epicardial leads(40 primary implants, 5 re-implants). Nineteen patients required pacing for surgically acquired heart block, 1 for surgically acquired sinus node dysfunction, 11 for congenital complete atrio-ventricular(AV) block, 7 for nonsurgical sinus node dysfunction, and...
Short-Term Results of Arterial Switch Operation for Transposition of Great Arteries
Yong Soo Yun, Yong Won Park, Chul Il Noh, Jung Yun Choi, Yong Jin Kim, Joon Ryang Rho, Kyung Pil Suh
Clin Exp Pediatr. 1992;35(6):795-803.   Published online June 15, 1992
The operative results of 50 cases who underwent arterial switch operation from January, 1986 to March, 1991 were evaluated. The results were summarized as follows ; 1) Three main combined cardiac defects of ASO cases were PDA(60%), VSD(56%) and ASD(46%), and most common type of VSD was perimembranous(64.3%) and most frequent pattern of coronary artery was usual pattern of TGA (84%). 2)...
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